Unravelling the Complexities of Neuroinflammatory Disorders
Summer 2024 | CNS Connections magazine
Autoimmune neuroinflammatory disorders are among the most dramatic and interesting diseases in child neurology. They can induce substantial neurological and psychiatric symptoms with a thunderclap onset, and they can lead…
Read MoreAbnormal Movements in Autism: Association or Causality?
Winter 2024 | CNS Connections magazine
Dr. Rujuta Wilson, an Assistant Professor of Child Psychiatry and Pediatric Neurology at UCLA, is exploring abnormal movements in Autism. When people think of autism, they usually think only of…
Read MoreA Marriage of Hematology and Neurology: Studying Sickle Cell Disease in the Pediatric Brain
Summer 2023 | CNS Connections magazine
As we all learned in medical school, sickle cell disease is an inherited hemoglobinopathy, caused by a single base pair mutation in the beta-globin gene. Although sickle cell disease was…
Read MoreOne More Problem with Childhood Obesity: Increased Risk of Bell Palsy
Winter 2023 | CNS Connections magazine
Association of overweight and obesity with Bell palsy in children. V. Breitling, A. Leha, S Schiller, et al. Pediatric Neurology 2023;139:43-48. What the researchers did: Childhood obesity is a substantial…
Read MoreLook Before You Leap: Test for Mimics of Small Vessel Primary Angiitis of the CNS Before Jumping to Brain Biopsy
Winter 2023 | CNS Connections magazine
Mimics of pediatric small vessel primary angiitis of the central nervous system. CM Stredny, MM Blessing, V Yi, et al. Annals of Neurology 2023;93:109-119. What the researchers did: Primary angiitis…
Read MoreLevetiracetam and Phenobarbital are Equal (and weak) in Efficacy for Neonatal Seizures
Winter 2023 | CNS Connections magazine
Levetiracetam versus phenobarbital for neonatal seizures: A retrospective cohort study. L. Battig, C. Dunner, D Cserpan et al. Pediatric Neurology 2023;138:62-70. What the researchers did: As all pediatric neurologists know,…
Read MoreUnraveling the Complex Interplay Among Epilepsy, Cognitive Impairment, and Sleep Disruption
Winter 2023 | CNS Connections magazine
Throughout most of medical history, epilepsy has been considered principally a problem of seizures. However, in recent years, the fact has become clear that epilepsy is more than just a…
Read MoreThe Importance of Intracellular Chloride Concentration and Neuronal Volume in Neonatal Seizures.
Spring/Summer 2019 | CNS Connections magazine
Neonatal seizures are a pernicious problem confronting child neurologists. While they are common and cause substantial morbidity, their pathophysiology is poorly understood. Most of the treatments for neonatal seizures consist…
Read MoreFocus on Young Researchers: Development of a Simple Blood Test for Mitochondrial Disorders
Spring/Summer 2018 | CNS Connections magazine
As all child neurologists know, “mitochondrial disorder” is frequently on the differential diagnosis for many children with neurological disease. However, determining whether a patient actually has a mitochondrial disorder is…
Read MoreThinking Outside the Lesion: Lesion Network Mapping
Winter 2018 | CNS Connections magazine
Important advances in neurology often begin with an intellectually curious physician observing an interesting patient. Such was the case that led Dr. Aaron Boes to the discovery of lesion network…
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