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Abnormal Movements in Autism: Association or Causality?

Winter 2023 | CNS Connections magazine

Dr. Rujuta Wilson, an Assistant Professor of Child Psychiatry and Pediatric Neurology at UCLA, is exploring abnormal movements in Autism. When people think of autism, they usually think only of…

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A Marriage of Hematology and Neurology: Studying Sickle Cell Disease in the Pediatric Brain

Summer 2023 | CNS Connections magazine

As we all learned in medical school, sickle cell disease is an inherited hemoglobinopathy, caused by a single base pair mutation in the beta-globin gene. Although sickle cell disease was…

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One More Problem with Childhood Obesity: Increased Risk of Bell Palsy

Winter 2023 | CNS Connections magazine

Association of overweight and obesity with Bell palsy in children. V. Breitling, A. Leha, S Schiller, et al. Pediatric Neurology 2023;139:43-48. What the researchers did: Childhood obesity is a substantial…

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Look Before You Leap: Test for Mimics of Small Vessel Primary Angiitis of the CNS Before Jumping to Brain Biopsy

Winter 2023 | CNS Connections magazine

Mimics of pediatric small vessel primary angiitis of the central nervous system. CM Stredny, MM Blessing, V Yi, et al. Annals of Neurology 2023;93:109-119. What the researchers did: Primary angiitis…

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Levetiracetam and Phenobarbital are Equal (and weak) in Efficacy for Neonatal Seizures

Winter 2023 | CNS Connections magazine

Levetiracetam versus phenobarbital for neonatal seizures: A retrospective cohort study. L. Battig, C. Dunner, D Cserpan et al. Pediatric Neurology 2023;138:62-70. What the researchers did: As all pediatric neurologists know,…

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Unraveling the Complex Interplay Among Epilepsy, Cognitive Impairment, and Sleep Disruption

Winter 2023 | CNS Connections magazine

Throughout most of medical history, epilepsy has been considered principally a problem of seizures.  However, in recent years, the fact has become clear that epilepsy is more than just a…

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The Importance of Intracellular Chloride Concentration and Neuronal Volume in Neonatal Seizures.

Spring/Summer 2019 | CNS Connections magazine

Neonatal seizures are a pernicious problem confronting child neurologists. While they are common and cause substantial morbidity, their pathophysiology is poorly understood. Most of the treatments for neonatal seizures consist…

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Focus on Young Researchers: Development of a Simple Blood Test for Mitochondrial Disorders

Spring/Summer 2018 | CNS Connections magazine

As all child neurologists know, “mitochondrial disorder” is frequently on the differential diagnosis for many children with neurological disease. However, determining whether a patient actually has a mitochondrial disorder is…

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Aaron Boes, MD, PhD

Thinking Outside the Lesion: Lesion Network Mapping

Winter 2018 | CNS Connections magazine

Important advances in neurology often begin with an intellectually curious physician observing an interesting patient. Such was the case that led Dr. Aaron Boes to the discovery of lesion network…

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Dr. Laura Lehman examines the neuroimaging studies of a child with stroke.

TIA and Stroke in Children

Winter 2017 | CNS Connections magazine

Transient ischemic attack (TIA) and stroke afflict millions of adults each year. In response, neurologists have conducted many clinical and basic science studies addressing the subject of cerebrovascular disease in…

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