The Importance of Intracellular Chloride Concentration and Neuronal Volume in Neonatal Seizures.
Spring/Summer 2019 | CNS Connections magazine
Neonatal seizures are a pernicious problem confronting child neurologists. While they are common and cause substantial morbidity, their pathophysiology is poorly understood. Most of the treatments for neonatal seizures consist…
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Focus on Young Researchers: Development of a Simple Blood Test for Mitochondrial Disorders
Spring/Summer 2018 | CNS Connections magazine
As all child neurologists know, “mitochondrial disorder” is frequently on the differential diagnosis for many children with neurological disease. However, determining whether a patient actually has a mitochondrial disorder is…
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Thinking Outside the Lesion: Lesion Network Mapping
Winter 2018 | CNS Connections magazine
Important advances in neurology often begin with an intellectually curious physician observing an interesting patient. Such was the case that led Dr. Aaron Boes to the discovery of lesion network…
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TIA and Stroke in Children
Winter 2017 | CNS Connections magazine
Transient ischemic attack (TIA) and stroke afflict millions of adults each year. In response, neurologists have conducted many clinical and basic science studies addressing the subject of cerebrovascular disease in…
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Improving Post-op Outcomes of Infants with Delayed Rewarming
Winter 2016 | CNS Connections magazine
To a greater extent than any of us would prefer, medicine is often practiced by habit. We do things the way they’ve always been done – because it’s the way…
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Brain Imaging: The Heart of the Matter for Newborns with Congenital Heart Disease
Fall 2015 | CNS Connections magazine
Child neurologists know that surgery on newborns with complex congenital heart disease can be accompanied by strokes or hypoxic brain injuries. Less well appreciated is the fact that half of…
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Uncovering the Mysteries of Brain Malformations and Epilepsy through the use of Resected Human Tissue
Winter 2015 | CNS Connections magazine
Laura Jansen, MD, PhD is a physician-scientist and a perfect example of how an individual with training as both a physician and neuroscientist can utilize that dual expertise to advance…
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Illuminating the Pathway through Signaling Pathways
August/September 2014 | CNS Connections magazine
Many of the most challenging diseases confronting child neurologists are genetic disorders that disrupt signaling pathways. These abnormal signaling pathways, when present in neurons and glia, can give rise to…
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Identification of the Gene Causing Sturge Weber Syndrome
April/May 2014 | CNS Connections magazine
Every now and then, conditions are ripe for a scientific breakthrough. These “conditions” include not only access to advanced technological tools that can facilitate a new discovery, but also (and,…
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Exploring Telemedicine for Pediatric Epilepsy
January/February 2014 | CNS Connections magazine
When a child has a chronic illness, just getting to a pediatric specialist’s office for a clinic visit can be a significant burden for the child and family. This is…
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